Carbonic anhydrase inhibitor anticonvulsants 

Carbonic anhydrase inhibitor anticonvulsants inhibit the enzyme carbonic anhydrase. Generally carbonic anhydrase inhibitors are used to treat epilepsy, glaucoma, mountain sickness, and is used as a diuretic.

Acetazolamide (ACZ), methazolamide (MZA), zonisamide (ZNS) and topiramate (TPM) are the most known CA inhibitors, belonging to the class of sulfonamides (Figure 8) that act as anticonvulsants in animal models of epilepsy as well as in epileptic patients.

Acetazolamide is also used as an anticonvulsant to control certain seizures in the treatment of epilepsy. It is also sometimes used to prevent or lessen some effects in mountain climbers who climb to high altitudes, and to treat other conditions as determined by your doctor.

Examples of carbonic inhibitor medications currently available are acetazolamide, methazolamide, dorzolamide, brinzolamide, diclofenamide, ethoxzolamide, and zonisamide. Acetazolamide is available in 125, 200, and 500 mg tablets. Patients with glaucoma may take nearly 250 mg to 1000 mg per day.