Gonadotropins
What are Gonadotropin releasing hormones?
Gonadotropin releasing hormone (GnRH) is a hormone produced in the hypothalamus and transported to the pituitary gland through the blood stream. GnRH controls the secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. Secretion of GnRH is controlled by neural input from other parts of the brain and in females particularly, through negative feedback by the sex steroids.
More potent analogues of GnRH (compared to endogenous GnRH) have been synthesized and are used to treat endometriosis, fibroids, infertility and prostate cancer.
Gonadotropin-releasing hormone causes the pituitary gland in the brain to make and secrete the hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In men, these hormones cause the testicles to make testosterone. In women, they cause the ovaries to make estrogen and progesterone.
List of Gonadotropin releasing hormones





