Hydrazide derivatives 

Hydrazide derivatives are highly specific antibacterial agents active only against Mycobacterium. They are bactericidal in action and work by interfering with metabolism of bacterial proteins, nucleic acids, carbohydrates, and lipids. Hydrazide derivatives are used in combination with other medicines, in the treatment or prevention of tuberculosis.

Hydrazide–hydrazone derivatives are present in many bioactive molecules and display a wide variety of biological activities, such as antibacterial, antitubercular, antifungal, anticancer, anti-inflammatory, anticonvulsant, antiviral, and antiprotozoal action.

Examples of commercialized bioactive hydrazine derivatives include cefazolin, rizatriptan, anastrozole, fluconazole, metazachlor, metamitron, metribuzin, paclobutrazol, diclobutrazole, propiconazole, hydrazine sulfate, diimide, triadimefon, and the diacylhydrazine insecticides.

Hydrazides and alkoxyamines are aldehyde-reactive chemical groups commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates) on glycoproteins and other polysaccharides.