Triazine anticonvulsants

What are Triazine anticonvulsants?

Triazine anticonvulsants act on presynaptic sodium channels and inhibit the release of excitatory neurotransmitters, glutamate and aspartate. Triazine anticonvulsants are used to treat absence seizures, partial seizures, tonic-clonic seizures and Lennox-Gastaut syndrome.

Triazine anticonvulsants act on presynaptic sodium channels and inhibit the release of excitatory neurotransmitters, glutamate and aspartate. Triazine anticonvulsants are used to treat absence seizures, partial seizures, tonic-clonic seizures and Lennox-Gastaut syndrome.

Examples of symmetrical triazines are chloro-s-triazines (simazine, atrazine, propazine, and cyanazine), the thiomethyl-s-triazines (ametryn, prometryn, terbutryn), and the methoxy-s-triazine (prometon). The most commonly used asymmetrical triazine is metribuzin.

Some broad-spectrum antiseizure medications include levetiracetam, lamotrigine, zonisamide and topiramate. Narrow-spectrum antiseizure medications: These medications mainly treat focal or partial seizures. Some narrow-spectrum antiseizure medications include ethosuximide, pregabalin, gabapentin and carbamazepine.