Antiadrenergic agents, centrally acting
What are Antiadrenergic agents, centrally acting?
Centrally acting antiadrenergic agents inhibit the stimulation of the central nervous system alpha-adrenergic receptors and decrease sympathetic stimulation to the blood vessels and the heart. They block the release and action of catecholamines (epinephrine, norepinephrine, dopamine), which are released in response to stress.
Centrally acting antiadrenergic agents make the heart beat slower and with less force, and relax the blood vessels. All these actions lead to a decrease blood pressure.
Centrally acting antiadrenergic agents are used to treat hypertension.
Examples of central-acting agents include: Clonidine (Kapvay, Nexiclon XR). Guanfacine (Intuniv). Methyldopa.
Centrally acting antiadrenergic agents make the heart beat slower and with less force, and relax the blood vessels. All these actions lead to a decrease blood pressure. Centrally acting antiadrenergic agents are used to treat hypertension.
Centrally acting drugs are a type of medicine that can be used to treat high blood pressure. Also known as central alpha antagonists, they work directly on the part of the brain that controls blood pressure. They include clonidine, methyldopa, and moxonidine.





