Antigonadotropic agents 

What are Antigonadotropic agents?

Antigonadotropic agents work by different mechanisms to inhibit the activity of gonadotropic hormones. Different agents are used to treat different medical conditions.

An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

Gonadotropin-releasing hormone causes the pituitary gland in the brain to make and secrete the hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In men, these hormones cause the testicles to make testosterone.

Antagon® (ganirelix acetate) and Cetrotide® (cetrorelix) are GnRH antagonists (hormonal drugs) which are currently approved for enhancing response to ovulation inducing drugs, and specifically to prevent premature ovulation. GnRH antagonists have not been shown to cause major side effects in humans so far.

The two principal gonadotropins in vertebrates are luteinizing hormone (LH) and follicle-stimulating hormone (FSH), although primates produce a third gonadotropin called chorionic gonadotropin (CG). LH and FSH are heterodimers consisting of two peptide chains, an alpha chain and a beta chain.

List of Antigonadotropic agents

Abacavir

Abacavir

Abatacept

Abatacept

Abavite

Abavite

Abecma

Abecma

Abecma

Abecma

Abelcet

Abelcet

Abilify

Abilify

Abilify

Abilify

Abilify

Abilify

Actemra

Actemra

Acyclovir

Acyclovir

Adderall

Adderall

Advil

Advil

Afinitor

Afinitor

Agamree

Agamree

Agamree

Agamree

Aimovig

Aimovig

Ajovy

Ajovy

Aldactone

Aldactone

Alecensa

Alecensa

Alecensa

Alecensa

Alfuzosin

Alfuzosin

Alprolix

Alprolix

Alunbrig

Alunbrig

Ambien

Ambien

AndroGel

AndroGel

Apixaban

Apixaban

Aptiom

Aptiom

Arimidex

Arimidex

Aromasin

Aromasin

Atarax

Atarax