Antimalarial combinations 

What are Antimalarial combinations?

Antimalarial combinations are products that contain more than one antimalarial agent in the one pill or dose. The different agents generally have different modes of action so attack the bacteria in different ways and in different stages of the life-cycle of the bacteria. These products give better antimicrobial action. Having more than one agent in one pill increases compliance and may prevent drug resistant strains of bacteria from emerging.

falciparum malaria. Fast acting artemisinin-based compounds are combined with a drug from a different class. Companion drugs include lumefantrine, mefloquine, amodiaquine, sulfadoxine/pyrimethamine, piperaquine and chlorproguanil/dapsone. Artemisinin derivatives include dihydroartemisinin, artesunate and artemether.

Introducing combination therapy in the African Region should improve efficacy and effectiveness of first-line antimalarial treatment as well as delay the development and selection of resistant parasites to the few currently available and efficacious drugs.

Combining chloroquine and proguanil is an option for CRPF when other 1st line antimalarials are contraindicated. Dosage should be calculated in terms of the base. The adult chloroquine dose is 300 mg base weekly (or in some countries 100 mg base daily). Pediatric preparations are available.

List of Antimalarial combinations

Abacavir

Abacavir

Abatacept

Abatacept

Abavite

Abavite

Abecma

Abecma

Abecma

Abecma

Abelcet

Abelcet

Abilify

Abilify

Abilify

Abilify

Abilify

Abilify

Actemra

Actemra

Acyclovir

Acyclovir

Adderall

Adderall

Advil

Advil

Afinitor

Afinitor

Agamree

Agamree

Agamree

Agamree

Aimovig

Aimovig

Ajovy

Ajovy

Aldactone

Aldactone

Alecensa

Alecensa

Alecensa

Alecensa

Alfuzosin

Alfuzosin

Alprolix

Alprolix

Alunbrig

Alunbrig

Ambien

Ambien

AndroGel

AndroGel

Apixaban

Apixaban

Aptiom

Aptiom

Arimidex

Arimidex

Aromasin

Aromasin

Atarax

Atarax