Antituberculosis combinations
What are Antituberculosis combinations?
Antituberculosis combinations are products with more than one drug, given simultaneously to treat tuberculosis. The different drugs have different mechanisms of action and are given together to avoid emergence of drug resistant strains of the Mycobacterium tuberculosis. Using medications with different mechanisms of action also targets the bacteria in different ways and makes treatment more effective.
Tuberculosis (TB) is caused by a bacterium (or germ) called Mycobacterium tuberculosis. When a person breathes in TB germs, the germs can settle in the lungs and begin to grow. From there, they can move through the blood to other parts of the body, such as the kidney, spine, and brain.
If TB of the lung is not treated early or if treatment isn’t followed, long-lasting (permanent) lung damage can result. TB can also cause infection of the bones, spine, brain and spinal cord, lymph glands, and other parts of the body.
TB is spread through the air from one person to another. TB bacteria are put into the air when a person with active TB disease of the lungs or throat coughs, sneezes, speaks, or sings. People nearby may breathe in these bacteria and become infected.





