Clobetasol is a highly potent steroid that helps reduce inflammation in the body.

Clodan (for the skin) is used to treat inflammation and itching caused by plaque psoriasis or skin conditions that respond to steroid medication.

Clodan may also be used for purposes not listed in this medication guide.

Clodan side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Clodan may cause serious side effects. Call your doctor at once if you have:

• worsening of your skin condition;
• redness, warmth, swelling, oozing, or severe irritation of any treated skin;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• high blood sugar–increased thirst, increased urination, dry mouth, fruity breath odor; or
• possible signs of absorbing Clodan through your skin–weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects of Clodan may include:

• burning, itching, swelling, or irritation of treated skin;
• dry or cracking skin;
• redness or crusting around your hair follicles;
• spider veins;
• stretch marks, thinning skin;
• rash or hives;
• acne; or
• temporary hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Starting Clodan? Read this first

Before taking this medicine

You should not use Clodan if you are allergic to it.

Tell your doctor if you have ever had:

• any type of skin infection;
• a skin reaction to any steroid medicine;
• liver disease; or
• an adrenal gland disorder.

Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

It is not known whether Clodan will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply clobetasol to your chest, avoid areas that may come into contact with the baby’s mouth.

Some brands or forms of this medicine are for use only in adults 18 and over.

Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

How should I use Clodan?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth.

Do not use Clodan on broken or infected skin. Also avoid using this medicine in open wounds.

Wash your hands before and after using clobetasol, unless you are using the medicine to treat the skin on your hands.

Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to.

Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.

If you are treating the diaper area, do not use plastic pants or tight-fitting diapers.

This medicine is for short-term use only (2 weeks, or up to 4 weeks for scalp psoriasis). Follow your doctor’s dosing instructions very carefully.

If you use clobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled.

Call your doctor if your symptoms do not improve, or if they get worse.

You should not stop using clobetasol suddenly. Follow your doctor’s instructions about tapering your dose.

Store at room temperature away from moisture and heat. Keep from freezing.

Clobetasol foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.

What happens if I miss a dose?

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line if anyone has accidentally swallowed the medication.

High doses or long-term use of Clodan can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using clobetasol topical?

Avoid applying Clodan to your face, underarms, or groin area.

Do not use this medicine to treat any condition that has not been checked by your doctor.

Avoid using other topical steroid medications on the areas you treat with clobetasol unless your doctor tells you to.

Clobetasol is a highly potent steroid that helps reduce inflammation in the body.

Clobex (for the skin) is used to treat inflammation and itching caused by plaque psoriasis or skin conditions that respond to steroid medication.

Clobex may also be used for purposes not listed in this medication guide.

Clobex side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Clobex may cause serious side effects. Call your doctor at once if you have:

• worsening of your skin condition;
• redness, warmth, swelling, oozing, or severe irritation of any treated skin;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• high blood sugar–increased thirst, increased urination, dry mouth, fruity breath odor; or
• possible signs of absorbing Clobex through your skin–weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects of Clobex may include:

• burning, itching, swelling, or irritation of treated skin;
• dry or cracking skin;
• redness or crusting around your hair follicles;
• spider veins;
• stretch marks, thinning skin;
• rash or hives;
• acne; or
• temporary hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Clobex if you are allergic to it.

Tell your doctor if you have ever had:

• any type of skin infection;
• a skin reaction to any steroid medicine;
• liver disease; or
• an adrenal gland disorder.

Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

It is not known whether Clobex will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply clobetasol to your chest, avoid areas that may come into contact with the baby’s mouth.

Clobex is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.

Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

How should I use Clobex?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth.

Do not use Clobex on broken or infected skin. Also avoid using this medicine in open wounds.

Wash your hands before and after using clobetasol, unless you are using the medicine to treat the skin on your hands.

Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to.

Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.

If you are treating the diaper area, do not use plastic pants or tight-fitting diapers.

This medicine is for short-term use only (2 weeks, or up to 4 weeks for scalp psoriasis). Follow your doctor’s dosing instructions very carefully.

If you use clobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled.

Call your doctor if your symptoms do not improve, or if they get worse.

You should not stop using clobetasol suddenly. Follow your doctor’s instructions about tapering your dose.

Store at room temperature away from moisture and heat. Keep from freezing.

Clobetasol foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.

What happens if I miss a dose?

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line if anyone has accidentally swallowed the medication.

High doses or long-term use of Clobex can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using clobetasol topical?

Avoid applying Clobex to your face, underarms, or groin area.

Do not use this medicine to treat any condition that has not been checked by your doctor.

Avoid using other topical steroid medications on the areas you treat with clobetasol unless your doctor tells you to.

What other drugs will affect Clobex?

Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Clobetasol is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various scalp and skin conditions, including plaque psoriasis (a skin disease in which red, scaly patches form on some areas of the body) and eczema (a skin disease that causes the skin to be dry and itchy and sometimes to develop red, scaly rashes). Clobetasol is also used to treat lichen sclerosus.

Clobetasol is a highly potent corticosteroid that helps reduce inflammation in the body. It works by activating natural substances in the skin to reduce swelling, redness, and itching.

Clobetasol is available in a cream, gel, ointment, lotion, solution, foam, or spray.

Warnings

Do not use clobetasol topical to treat acne, rosacea, or a rash around the mouth.

Use care when putting on a large part of the skin or where there are open wounds. Talk with the doctor.

Clobetasol may cause harm if swallowed. If swallowed, call a doctor or poison control center right away.

This drug may raise the chance of cataracts or glaucoma. Talk with your doctor.

It may affect growth in children and teens in some cases. They may need regular growth checks.

If you are breast-feeding, do not apply clobetasol cream, gel, ointment, lotion, solution, foam or spray to the nipple or the area around it.

Before taking this medicine

You should not use clobetasol topical if you are allergic to it.

To make sure this drug is safe for you, tell your doctor if you have ever had:

• any type of skin infection;
• a skin reaction to any steroid medicine;
• liver disease; or
• an adrenal gland disorder.

Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

It is not known whether clobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply this drug to your chest, avoid areas that may come into contact with the baby’s mouth.

Clobetasol is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.

Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

How should I use clobetasol?

Use this drug exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth.

Do not use clobetasol on broken or infected skin. Also avoid using this medicine in open wounds.

Wash your hands before and after using this drug, unless you are using the medicine to treat the skin on your hands.

Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to.

Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.

If you are treating the diaper area, do not use plastic pants or tight-fitting diapers.

This medicine is for short-term use only (2 weeks, or up to 4 weeks for scalp psoriasis). Follow your doctor’s dosing instructions very carefully.

If you use clobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled.

Call your doctor if your symptoms do not improve, or if they get worse.

You should not stop using this drug suddenly. Follow your doctor’s instructions about tapering your dose.

Store at room temperature away from moisture and heat. Keep from freezing.

Clobetasol foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.

What happens if I miss a dose?

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line if anyone has accidentally swallowed the medication.

High doses or long-term use of clobetasol can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using clobetasol?

Avoid applying clobetasol topical to your face, underarms, or groin area. However, clobetasol can be applied to the groin area, under strict medical supervision, to treat lichen sclerosus.

Do not use this medicine to treat any condition that has not been checked by your doctor.

Avoid using other topical steroid medications on the areas you treat with clobetasol unless your doctor tells you to.

Clobetasol side effects

Get emergency medical help if you have signs of an allergic reaction to clobetasol: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• worsening of your skin condition;
• redness, warmth, swelling, oozing, or severe irritation of any treated skin;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• high blood sugar – increased thirst, increased urination, dry mouth, fruity breath odor; or
• possible signs of absorbing this medicine through your skin – weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects may include:

• burning, itching, swelling, or irritation of treated skin;
• dry or cracking skin;
• redness or crusting around your hair follicles;
• spider veins;
• stretch marks, thinning skin;
• rash or hives;
• acne; or
• temporary hair loss.

Bryhali is a high-potency, Class I corticosteroid lotion that may be used by adults to reduce inflammation and itching caused by plaque psoriasis. It contains 0.01% halobetasol propionate.

Bryhali was approved on November 6, 2018. It contains a lower concentration than other halobetasol propionate lotions which limits its risk of side effects.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Bryhali (halobetasol propionate 0.01% lotion) is a highly potent, Class I corticosteroid that can be absorbed through the skin into the bloodstream and cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency, including Cushing’s syndrome, hyperglycemia, and glucosuria. Do not use for longer than 2 weeks and do not exceed the recommended dose. Periodic monitoring for HPA suppression may be required.

Before taking this medicine

You should not use halobetasol topical if you are allergic to it.

Bryhali should not be applied to lesions that are exuding serum or to skin folds (where two areas of skin touch each other).

Tell your doctor if you have ever had:

• any type of skin infection;
• a skin reaction to any steroid medicine;
• liver disease; or
• an adrenal gland disorder.

Topical corticosteroids can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

Children are more susceptible to systemic absorption of topical corticosteroids. Bryhali is not approved for use by anyone younger than 18 years old.

It is not known whether halobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant. If you are instructed to use Bryhali, use only a small amount for the shortest time possible.

It may not be safe to breastfeed while using this medicine. If you are instructed to use Bryhali, use only a small amount for the shortest time possible. Do not apply to the breasts.

How do I use Bryhali?

Apply Bryhali exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Do not take it by mouth or use it intravaginally. Topical medicine is for use only on the skin. Do not use on open wounds or sunburned, windburned, dry, or irritated skin. Rinse with water if Bryhali gets in your eyes or mouth.

• Wash your hands before and after using Bryhali, unless you are using this medicine to treat the skin on your hands.
• Apply a thin layer of Bryhali lotion to the affected areas once daily. Rub in gently and completely. Do not apply this medicine over a large area of skin unless your doctor has told you to.

Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.

Bryhali lotion is for short-term use only (up to 8 weeks). Follow your doctor’s dosing instructions very carefully.  Clinical trials have shown Bryhali continues to provide relief from psoriasis for up to 4 weeks after stopping using it.

Call your doctor if your symptoms do not improve after 8 weeks, or if they get worse. Stop using the product if your symptoms improve sooner.

What happens if I miss a dose?

Apply the product as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line if anyone has accidentally swallowed the medication.

High doses or long-term use of Bryhali lotion can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using Bryhali?

• Avoid applying Bryhali to your face, scalp, underarms, or groin area. Do not use it to treat any skin condition that has not been checked by your doctor.
• Avoid using other topical steroid medications on the areas you treat with Bryhali unless your doctor tells you to.
• Do not use more than 50 grams per week.

What are the side effects of Bryhali?

Get emergency medical help if you have signs of an allergic reaction to Bryhali such as hives; difficulty breathing; or swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• worsening of your skin condition;
• redness, warmth, swelling, oozing, or severe irritation of any treated skin;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• high blood sugar – increased thirst, increased urination, dry mouth, fruity breath odor; or
• possible signs of absorbing this medicine through your skin – weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Common Bryhali side effects may include:

• upper respiratory tract infection
• burning, stinging, itching, or dryness of treated skin
• high blood sugar levels.

Other side effects that may occur with topical corticosteroids include:

• acne
• discoloration of the skin where the tape has been applied
• dryness
• excessive hair growth
• miliaria
• ophthalmic side effects such as cataracts or glaucoma
• perioral dermatitis and allergic contact dermatitis
• redness or crusting around your hair follicles (folliculitis)
• skin thinning
• spider veins
• stretch marks.

Topical corticosteroids can cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency.

If you develop a skin infection while using Bryhali your doctor may give you an antimicrobial cream to use as well. If this does not resolve the infection, your doctor may discontinue the tape until the infection has cleared.

Betamethasone is a highly potent steroid that prevents the release of substances in the body that cause inflammation.

Betamethasone topical (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as eczema or psoriasis.

Betamethasone topical is available in a cream, gel, ointment, lotion, foam, or spray.

Topical betamethasone formulations are usually formulated with one of two salts: betamethasone dipropionate or betamethasone valerate. The potency of betamethasone formulations can vary depending on which salt is used – dipropionate or valerate.

Betamethasone dipropionate contains two esters – this makes it more fat soluble and increases its ability to penetrate the skin better. This makes it more potent than betamethasone valerate, which only contains one ester.

The absorption and potency of a topical steroid can also vary depending on the vehicle used to deliver the steroid (such as a cream, gel, lotion, or ointment) and if it has been augmented or not. Augmentation refers to enhancing the vehicle with a substance, such as propylene glycol, to allow it to penetrate the skin more quickly and work faster. For example, augmented betamethasone dipropionate 0.05% ointment or gel is a Class 1 (highly potent) topical steroid, but the augmented lotion or cream and regular betamethasone dipropionate ointment is Class 2.

Potency of betamethasone preparations

Class 1 (highly potent)

• Augmented betamethasone dipropionate 0.05% ointment
• Augmented betamethasone dipropionate 0.05% gel

Class 2 (potent)

• Augmented betamethasone dipropionate 0.05% lotion
• Augmented betamethasone dipropionate 0.05% cream (0.05%)
• Regular betamethasone dipropionate 0.05% ointment

Class 3 (upper medium potency)

• Regular betamethasone dipropionate cream 0.05%

Class 4 and 5 (medium potency)

• Betamethasone valerate foam 0.12%
• Regular betamethasone dipropionate spray 0.05%

Warnings

Do not use betamethasone longer than you have been told to by your doctor. Use care when using on a large part of the skin. Talk with your doctor.

Do not use to treat diaper rash or redness. Avoid applying betamethasone cream, gel, ointment, lotion, foam, or spray to the diaper area.

Different brands of betamethasone may be for use in different ages of children. Talk with the doctor before using betamethasone cream, gel, ointment, lotion, foam, or spray on a child.

If you are breastfeeding, do not apply betamethasone cream, gel, ointment, lotion, foam, or spray to the nipple or the area around it.

Betamethasone may raise the chance of cataracts or glaucoma. Talk to your doctor.

Before taking this medicine

You should not use betamethasone if you are allergic to it.

To make sure betamethasone is safe for you, tell your doctor if you have ever had:

• skin irritation after using steroid medicine;
• thinning of the skin where you will apply betamethasone;
• cataracts or glaucoma;
• diabetes;
• liver disease;
• adrenal gland problems; or
• any type of skin infection.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breastfeed a baby while you are using this medicine. Ask your doctor about any risks. If you apply betamethasone to your chest, avoid areas that may come into contact with the baby’s mouth.

Do not use betamethasone on a child without a doctor’s advice. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

Diprolene is not approved for use by anyone younger than 13 years old. Sernivo and Luxiq are not approved for anyone younger than 18 years old.

How should I use betamethasone ?

Use betamethasone cream, gel, ointment, lotion, foam, or spray exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Do not take by mouth. Topical medicine is for use only on the skin. Do not use on open wounds or on sunburned, windburned, dry, or irritated skin. Rinse with water if this medicine gets in your eyes or mouth.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Wash your hands before and after using this medicine, unless you are using the medicine to treat the skin on your hands.

Apply a small amount to the affected area and rub it gently into the skin. Do not apply betamethasone cream, gel, ointment, lotion, foam, or spray over a large area of skin.

Do not cover the treated skin area unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.

Use betamethasone regularly to get the most benefit. Stop using the medicine once your symptoms clear up.

Call your doctor if your skin condition does not improve after 2 weeks, or if it gets worse.

Do not use Diprolene for longer than 2 weeks in a row. Do not use Sernivo or Luxiq for longer than 4 weeks.

Store at room temperature away from moisture and heat.

The foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.

Dosing information

Usual Adult Dose for Dermatitis:

Cream, gel, ointment:

• Apply a thin film topically to the affected area 1 or 2 times a day
• Foam, lotion: Apply topically twice a day (morning and night)

Comments:

• Treatment should be discontinued when control is achieved; if no improvement is seen within 2 weeks, reassessment may be necessary.
• Occlusive dressings should not be used unless directed by a healthcare provider.

Use: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses

Usual Adult Dose for Plaque Psoriasis:

Spray:

• Apply topically to affected skin areas twice a day; rub in gently
• Duration of Treatment: Up to 4 weeks

Comments:

• Discontinue therapy when control is achieved; treatment beyond 4 weeks is not recommended.

Use: For the treatment of mild to moderate plaque psoriasis.

Usual Pediatric Dose for Dermatitis:

12 years or older:

• Cream, gel, ointment: Apply a thin film topically to the affected area 1 or 2 times a day
  Foam, lotion: Apply topically twice a day (morning and night)

Comments:

• Treatment should be discontinued when control is achieved; if no improvement is seen within 2 weeks, reassessment may be necessary.
• Occlusive dressings should not be used unless directed by a healthcare provider.
• Administration of topical corticosteroids to pediatric patients should be limited to the least amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may interfere with the growth and development of children.

Use: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses

What other drugs will affect betamethasone?

Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

What happens if I miss a dose?

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line if anyone has accidentally swallowed the medication.

Long term use of high doses can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using betamethasone?

Do not get betamethasone topical in your eyes. If contact does occur, rinse with water.

Avoid applying betamethasone to the skin of your face, underarms, or groin area without your doctor’s instruction.

Do not use betamethasone to treat any condition that has not been checked by your doctor.

Betamethasone side effects

Get emergency medical help if you have signs of an allergic reaction to betamethasone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using betamethasone and call your doctor at once if you have:

• severe skin irritation where the medicine was applied; or
• signs of skin infection (swelling, redness, warmth, oozing).

Your skin can absorb topical steroid medicine, which may cause steroid side effects throughout the body. Stop using betamethasone and call your doctor if you have:

• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• slow wound healing, thinning skin, increased body hair;
• increased thirst or urination, dry mouth, fruity breath odor;
• weight gain, puffiness in your face; or
• muscle weakness, tired feeling, depression, anxiety, feeling irritable.

Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common betamethasone side effects may include:

• itching, redness, burning, stinging, or blistering of treated skin;
• skin bruising or shiny appearance; or
• folliculitis (redness or crusting around your hair follicles).

What is halobetasol topical?

Halobetasol topical is a super high potency, Class I corticosteroid product that is applied to the skin to reduce inflammation and itching caused by plaque psoriasis or other skin conditions that respond to corticosteroid medication.

Halobetasol topical is available as a cream, ointment, lotion, or foam:

• Halobetasol propionate 0.05% foam: Lexette foam           
• Halobetasol propionate 0.05% cream/ointment/lotion: Ultravate cream/ointment/lotion
• Halobetasol propionate 0.01% lotion: Bryhali lotion

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Halobetasol (halobetasol propionate) is a highly potent, Class I corticosteroid that can be absorbed through the skin into the bloodstream and cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency, including Cushing’s syndrome, hyperglycemia, and glucosuria. Do not use for longer than 2 weeks and do not exceed the recommended dose. Periodic monitoring for HPA suppression may be required.

Before taking this medicine

You should not use halobetasol topical if you are allergic to it.

Halobetasol topical should not be applied to lesions that are exuding serum or to skin folds (where two areas of skin touch each other).

Tell your doctor if you have ever had:

• any type of skin infection;
• a skin reaction to any steroid medicine;
• liver disease; or
• an adrenal gland disorder.

Topical corticosteroids can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

Children are more susceptible to systemic absorption of topical corticosteroids. Most preparations of halobetasol topical are not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.

It is not known whether halobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant. If you are instructed to use halobetasol topical, use a small amount for the shortest time possible.

It may not be safe to breastfeed while using this medicine. If you are instructed to use halobetasol topical, use a small amount for the shortest time possible. Do not apply to the breasts.

How do I use halobetasol topical?

Use halobetasol exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Do not take it by mouth. Topical medicine is for use only on the skin. Do not use on open wounds or sunburned, windburned, dry, or irritated skin. Rinse with water if halobetasol gets in your eyes or mouth.

Wash your hands before and after using halobetasol, unless you are using this medicine to treat the skin on your hands.

Shake the foam before each use.

• Apply a thin layer of halobetasol topical to the affected area once or twice daily as directed by your doctor. Rub in gently and completely. Do not apply this medicine over a large area of skin unless your doctor has told you to.
• Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.
• Halobetasol is for short-term use only (2 weeks, or up to 8 weeks for psoriasis). Follow your doctor’s dosing instructions very carefully. Do not use more than 50 grams per week.

Call your doctor if your symptoms do not improve after 2 weeks (8 weeks for psoriasis), or if they get worse. Stop using the product if your symptoms improve sooner.

What happens if I miss a dose?

Apply the product as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line if anyone has accidentally swallowed the medication.

High doses or long-term use of halobetasol topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using halobetasol topical?

• Avoid applying halobetasol topical to your face, scalp, underarms, or groin area.
• Do not use halobetasol topical to treat any skin condition that has not been checked by your doctor.
• Avoid using other topical steroid medications on the areas you treat with halobetasol unless your doctor tells you to.

What are the side effects of halobetasol topical?

Get emergency medical help if you have signs of an allergic reaction to halobetasol, such as hives; difficulty breathing; or swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• worsening of your skin condition;
• redness, warmth, swelling, oozing, or severe irritation of any treated skin;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• high blood sugar – increased thirst, increased urination, dry mouth, fruity breath odor; or
• possible signs of absorbing this medicine through your skin – weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Common halobetasol side effects may include:

• burning, stinging, itching, or dryness of treated skin;
• pain where the foam was applied;
• redness or crusting around your hair follicles;
• stretch marks;
• spider veins;
• headache; or
• cold symptoms such as stuffy nose, sneezing, and a sore throat.

What is hydrocortisone cream?

Hydrocortisone cream is used to treat eczema, dermatitis, psoriasis, hemorrhoids, insect bites or stings, and other skin conditions to help relieve itchy or inflamed skin. It is also available as hydrocortisone ointment, suppositories, gel, and lotion. Hydrocortisone is a steroid medicine that works by decreasing inflammation and reducing an overactive immune system.

Hydrocortisone cream and skin products should only be used on skin conditions that respond to steroids.

Hydrocortisone creams, suppositories, and other topical products may contain other active ingredients, including antibiotics neomycin and polymyxin B sulfate when used for inflamed, infected skin, or hydrocortisone with pramoxine for hemorrhoids.

Hydrocortisone, hydrocortisone butyrate, and hydrocortisone acetate are different medicines. Hydrocortisone butyrate 0.1% (Locoid) is stronger or more potent than hydrocortisone 2.5%, 1% and 0.5%. Hydrocortisone acetate and hydrocortisone are both mild steroids.

Hydrocortisone ointment is used on very dry skin and creates a barrier to lock in moisture. This also helps the active ingredient penetrate the skin, so it is more potent than creams and lotions. Creams are easier to apply to the skin, are absorbed quickly, and help keep the skin moisturized. Lotions are lighter and easier to apply to large areas of the body, hairy areas, or weeping skin. Gels are often used on the scalp because they don’t leave the hair greasy.

Hydrocortisone tablets are used to treat asthma, allergic reactions, arthritis, inflammatory bowel diseases, adrenal insufficiency, lupus, certain cancers, and inflammatory conditions. It works to decrease inflammation, replace cortisol, or improve an overactive immune system.

Hydrocortisone side effects

Common hydrocortisone cream side effects (topical use)

Common hydrocortisone cream side effects are skin redness, itching, stinging, rash, redness or crusting around your hair follicles, burning, dryness, or other irritation of treated skin, itching, or irritation around your mouth, appearance and color changes in treated skin, signs of skin infection (swelling, redness, warmth, oozing), numbness, tingling, or burning pain.

Serious hydrocortisone cream side effects (topical use)

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Hydrocortisone side effects can occur if your skin absorbs topical steroid medicine. Tell your doctor if you have:

• swelling, weight gain (especially in your face or your upper back and torso);
• thinning skin, stretch marks, acne, increased facial hair;
• irregular menstrual periods, changes in sexual function, or
• memory problems, feeling irritable.

Hydrocortisone skin products can cause other serious side effects. Call your doctor at once if you have:

• worsening of your skin condition;
• pain, tenderness, headache;
• blurred vision, eye pain or redness, seeing halos around lights;
• high blood sugar–increased thirst, increased urination, dry mouth, fruity breath odor; or
• increased adrenal gland hormones–hunger, weight gain, swelling, skin discoloration, slow wound healing, sweating, acne, increased body hair, tiredness, mood changes, muscle weakness, missed menstrual periods, sexual changes.

Children can absorb larger amounts of hydrocortisone through the skin and may be more likely to have side effects.

Common hydrocortisone side effects (tablets)

Common hydrocortisone tablet side effects include fluid retention, alteration in glucose tolerance, elevation in blood pressure, behavioral and mood changes, increased appetite, and weight gain.

Serious hydrocortisone side effects (tablets)

Serious hydrocortisone tablet side effects include adrenal crisis, immunosuppression and increased risk of infection, slow growth, Cushing’s syndrome, decrease in bone mineral density, psychiatric side effects, ophthalmic adverse reactions, gastrointestinal adverse reactions, vaccinations and risk of Kaposi’s sarcoma.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA .

Warnings

Warnings for OTC hydrocortisone cream

Do not use it in the eyes, for diaper rash, or for external genital or feminine itching if you have a vaginal discharge. Do not use more than the recommended daily dosage unless directed by a doctor

Stop using this product and consult a doctor if your condition worsens or if symptoms persist for more than 7 days or clear up and occur again within a few days (do not continue to use this or any other hydrocortisone product for longer than 7 days, unless prescribed by a doctor).

Stop using this product and consult a doctor if bleeding occurs due to anal itching.

Prolonged use of topical corticosteroids may cause atrophy of the epidermis and subcutaneous tissue; these effects are most likely to occur (even with short-term use) in intertriginous (e.g., axilla, groin), flexor, and facial areas.

If a skin infection develops or is present, anti-infective therapy should be started. If it does not respond promptly, discontinue topical corticosteroid therapy until the infection has been controlled.

Warning for hydrocortisone tablets

Hydrocortisone Tablets may suppress the immune system and increase the risk of infection. Corticosteroid-associated infections can be mild but can be severe and, at times, fatal. The rate of infectious complications increases with increasing corticosteroid dosages.

Prolonged use of corticosteroids may cause eye side effects, including posterior subcapsular cataracts and glaucoma with possible damage to the optic nerves. It may also enhance the establishment of secondary ocular infections due to fungi or viruses.

Kaposi’s sarcoma has been reported to occur in patients receiving corticosteroid therapy, most often for chronic condition.

Average and large doses of hydrocortisone or cortisone can elevate blood pressure, cause salt and water retention, and increase potassium excretion.

Vaccinations. Administration of live or live, attenuated vaccines is contraindicated in patients receiving immunosuppressive doses of corticosteroids. Killed or inactivated vaccines may be administered to patients receiving immunosuppressive doses of corticosteroids; however, the response to such vaccines may be diminished. Indicated immunization procedures may be undertaken in patients receiving nonimmunosuppressive doses of corticosteroids.

Before taking this medicine

Hydrocortisone cream

You should not use hydrocortisone topical if you are allergic to it.

Tell your doctor if you have or have ever had:

• any type of skin infection;
• a skin reaction to any steroid medicine;
• cataract or glaucoma;
• thinning of the skin where you will apply hydrocortisone topical;
• problems with your adrenal gland; or
• liver disease.

Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

Pregnancy

Tell your healthcare provider if you are pregnant, plan to become pregnant or become pregnant as it is not known if hydrocortisone topical will harm an unborn baby.

Breastfeeding

Ask your healthcare provider if it is safe to breastfeed while using this medicine.

Hydrocortisone tablets

You should not use hydrocortisone if you are allergic to hydrocortisone or corticosteroids or if you have a systemic fungal infection.

Steroids can weaken your immune system, making it easier to get an infection or worsen an infection you already have. Tell your doctor about any illness or infection you had within the past several weeks.

Tell your doctor if you have ever had:

• heart disease, high blood pressure;
• tuberculosis;
• kidney disease;
• cirrhosis or other liver disease;
• a thyroid disorder;
• low bone mineral density (osteoporosis);
• stomach ulcers, ulcerative colitis, diverticulitis;
• diabetes;
• a colostomy or ileostomy;
• depression or mental illness;
• glaucoma or cataracts;
• herpes infection of the eyes; or
• a muscle disorder such as myasthenia gravis.

Long-term oral use of steroids may lead to bone loss (osteoporosis), especially if you smoke, do not exercise, do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis.

Pregnancy

It is not known whether hydrocortisone tablets or capsules will harm an unborn baby. However, using this medicine during pregnancy may cause a hormone deficiency in the newborn. Tell your doctor if you are pregnant or plan to become pregnant.

Breastfeeding

Ask a doctor if it is safe to breastfeed while using this medicine.

How should I use hydrocortisone cream?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Wash your hands before and after applying this medicine unless you are using it to treat a hand condition.

Do not take it by mouth. Topical medicine is for use only on the skin.

Apply a thin layer of hydrocortisone cream, ointment, lotion, or gel to the affected skin and rub it in gently. Do not apply this medicine over a large skin area unless your doctor has told you to.

Apply rectal creams and ointments externally to the anal area; some commercially available creams also may be applied externally to the anogenital areas.

For scalp conditions, part the hair and apply a small amount of lotion or solution directly to the affected area; rub gently into the scalp. Maintain usual hair care, but do not wash out the lotion immediately after application. Alternatively, for scalp dermatoses, apply aerosol to dry scalp after shampooing.

Do not cover treated skin with a bandage unless your doctor tells you to.

For hydrocortisone lotion and spray shake well just before each use.

If you are treating the diaper area, do not use plastic pants or tight-fitting diapers.

You may need medical tests to be sure this medicine is not causing harmful effects.

You may need blood or urine tests while using this medicine.

Stop using OTC hydrocortisone skin products and call your doctor if your symptoms do not improve after using this medicine for 7 days, or if your symptoms get worse or get better, and then come back in a few days.

Store at room temperature, away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.

How should I take hydrocortisone tablets or capsules?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take with food if hydrocortisone upsets your stomach.

Do not swallow an Alkindi Sprinkle capsule whole. Open the capsule and pour the medicine granules onto the tongue before swallowing. You may also mix the granules with soft food such as yogurt or applesauce (not with liquid). Swallow the mixture right away without chewing.

Drink water right after taking the Alkindi Sprinkle granule mixture. If giving this medicine to a baby, give infant formula or breast milk.

If you have trouble sleeping, you may need to take this medicine early in the day. Follow your doctor’s dosing instructions very carefully.

Your dose needs may change if you have a serious illness, fever or infection, surgery or a medical emergency. Tell your doctor about any such situation that affects you.

Your doctor will need to check your progress on a regular basis.

You should not stop taking hydrocortisone suddenly. Follow your doctor’s instructions about tapering your dose.

Store at room temperature away from moisture, heat, and light.

Wear a medical alert tag or carry an ID card to let others know you use steroid medication.

What happens if I miss a dose?

Skin products: Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

Tablets or capsules: Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line if anyone has accidentally swallowed the medicine.

Skin products: High doses or long-term use of hydrocortisone topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

Hydrocortisone tablets or capsules:

High doses or long-term use of steroid medicine can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using hydrocortisone?

Skin products

• Do not use hydrocortisone topical to treat any skin condition that has not been checked by your doctor.
• Avoid applying hydrocortisone topical to the skin of your face, underarms, or groin area unless your doctor has told you to.
• Avoid using other medications on the areas you treat with hydrocortisone skin products unless your doctor tells you to.
• Do not get hydrocortisone topical in your eyes. If contact does occur, rinse with water.

Hydrocortisone oral products

• Avoid receiving a “live” vaccine. The vaccine may not work as well while you are using hydrocortisone.
• Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chickenpox or measles. These conditions can be serious or even fatal in people who are using hydrocortisone.

What other drugs will affect hydrocortisone?

Skin products

Medicine used on the skin is not likely to be affected by other drugs you use, but many drugs can interact. Tell your doctor about all your current medicines, including prescription and over-the-counter medicines, vitamins, and herbal products.

Hydrocortisone oral products

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your current medicines. Many drugs can affect hydrocortisone tablets and capsules, especially:

• birth control pills or hormone replacement therapy;
• heart medication;
• insulin or oral diabetes medicine;
• medicine to treat an infection;
• seizure medication;
• a blood thinner such as warfarin (Coumadin, Jantoven); or
• NSAIDs (nonsteroidal anti-inflammatory drugs)–aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

What is Impoyz cream?

Impoyz cream is a highly potent topical steroid that may be applied to the skin to reduce inflammation and itching caused by moderate to severe plaque psoriasis in adults aged 18 years and older. It contains clobetasol propionate 0.025% and should not be used for longer than 2 weeks.

Impoyz cream is specially formulated using an ingredient called Transcutol that enhances the solubility of clobetasol and its permeation into plaques. This means that Impoyz is just as effective as other clobetasol creams but with half the usual concentration of clobetasol, which decreases its risk of side effects including absorption into the bloodstream. Transcutol is also less disrupting to the skin’s lamellar structure (a layer of lipids and water in the stratum corneum) than propylene glycol, which is traditionally used in creams to enhance drug solubility.

Impoyz was FDA approved on December 1, 2017.

Warnings

Impoyz cream contains clobetasol propionate which can be absorbed through the skin into the bloodstream and cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency, including Cushing’s syndrome, hyperglycemia, and glucosuria. Do not use for longer than 2 weeks and do not exceed the recommended dose. Periodic monitoring for HPA suppression may be required.

Occlusive dressings should not be used unless under the advice of the doctor because these increase the risk of side effects.

Before taking this medicine

You should not use Impoyz if you are allergic to it.

Tell your doctor if you have ever had:

• any type of skin infection;
• a skin reaction to any steroid medicine;
• liver disease; or
• an adrenal gland disorder.

Topical corticosteroids can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

Children are more susceptible to systemic absorption of topical corticosteroids and Impoyz is not for use in children or young adults under the age of 18.

It is not known whether Impoyz will harm an unborn baby. Tell your doctor if you are pregnant. If you are instructed to use Impoyz cream, use only a small amount and for the shortest time possible.

It may not be safe to breastfeed while using this medicine. If you are instructed to use Impoyz cream, use only a small amount and for the shortest time possible. Do not apply to the breasts.

How do I use Impoyz cream?

Apply a thin layer of Impoyz to the affected areas twice a day. Rub in gently and completely. Apply exactly as directed.

• Wash your hands after applying.
• Stop using Impoyz cream when your psoriasis is controlled but do not use it for longer than 2 weeks. If 2 weeks have passed and your psoriasis has not got any better, stop applying the cream and contact your doctor.
• If your psoriasis gets better earlier than 2 weeks, stop using Impoyz.
• Do not exceed 50g per week.
• Do not use it if your skin is thin where you want to apply it.
• Do not bandage, cover, or wrap your skin where you have applied Impoyz unless your doctor has told you to do so.
• Do not use it on your face, scalp, armpits, groin, or skin folds.
• Do not use other corticosteroid products while using Impoyz.

Impoyz should only be applied to the skin. Do not take by mouth, apply near your eyes, or insert it.

What are the side effects of Impoyz cream?

The most common side effect of Impoyz Cream includes discoloration of the skin where you have applied it.

Topical corticosteroids can cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency.

Other side effects reported with topical corticosteroids include:

• acne
• allergic contact dermatitis
• burning, itching, swelling, or irritation of treated skin
• dry or cracking skin
• redness or crusting around your hair follicles
• spider veins
• stretch marks, thinning skin
• rash or hives
• temporary hair loss.

If you develop a skin infection while using Impoyz your doctor may give you an antimicrobial cream to use as well. If this does not resolve the infection, your doctor may discontinue Impoyz until the infection has cleared.

Possible signs that you may be absorbing this medicine through your skin include weight gain in your face and shoulders, increased body hair, tiredness, mood changes, menstrual changes, and sexual changes.

What is Kenalog topical?

Kenalog contains triamcinolone, a potent corticosteroid. Triamcinolone reduces the actions of chemicals in the body that cause inflammation.

Kenalog topical is used to treat the inflammation caused by a number of conditions such as allergic reactions, eczema, and psoriasis. The dental paste form of triamcinolone (Kenalog Orabase) is used to treat mouth ulcers.

Kenalog topical may also be used for purposes not listed in this medication guide.

Warnings

Use Kenalog exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended.

Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with Kenalog can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor’s instructions.

Avoid using Kenalog on your face, near your eyes, or on body areas where you have skin folds or thin skin.

Do not use Kenalog on a child without a doctor’s advice. Children are more sensitive to the effects of Kenalog.

Kenalog topical will not treat a bacterial, fungal, or viral skin infection.

Contact your doctor if your condition does not improve or if it gets worse after using this medication for several days.

Before using Kenalog

Do not use Kenalog if you are allergic to triamcinolone.

To make sure you can safely use Kenalog, tell your doctor if you have any of these other conditions:

• any skin infection, especially tuberculosis infection of the skin;
• chicken pox or herpes infection (including cold sores);
• diabetes; or
• a stomach ulcer.

It is not known whether Kenalog will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether triamcinolone passes into breast milk or if it could harm a nursing baby. Do not use Kenalog without telling your doctor if you are breastfeeding a baby. Do not use this medication on a child without a doctor’s advice. Children are more sensitive to the effects of Kenalog.

How should I use Kenalog?

Use Kenalog exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Kenalog topical will not treat a bacterial, fungal, or viral skin infection.

Wash your hands before and after each application, unless you are using Kenalog to treat a hand condition.

Apply a small amount to the affected area and rub it gently into the skin.

Avoid using Kenalog on your face, near your eyes or mouth, or on body areas where you have skin folds or thin skin.

If you are using the dental paste, apply the medication in a thin layer, just enough to cover the mouth ulcer. The paste may stick better if you dry the mouth ulcer before applying the medication.

Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with Kenalog can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor’s instructions. Contact your doctor if your condition does not improve or if it gets worse after using this medication for several days. It is important to use Kenalog regularly to get the most benefit.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line , especially if anyone has accidentally swallowed this medicine. An overdose of Kenalog applied to the skin is not expected to produce life-threatening symptoms.

What should I avoid?

Avoid getting Kenalog in your eyes, mouth, and nose, or on your lips. If it does get into any of these areas, wash with water. Do not use Kenalog on sunburned, windburned, irritated, or broken skin. Also avoid using Kenalog in open wounds.

Avoid using skin products that can cause irritation, such as harsh soaps or skin cleansers, or skin products with alcohol, spices, astringents, or lime. Avoid using other medications on the areas you treat with Kenalog unless your doctor tells you to.

Kenalog side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Kenalog: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these signs that you may be absorbing triamcinolone through your skin or gums:

• blurred vision, or seeing halos around lights;
• uneven heartbeats;
• mood changes;
• sleep problems (insomnia);
• weight gain, puffiness in your face; or
• feeling tired.

Less serious Kenalog side effects may include:

• skin redness, burning, itching, or peeling;
• thinning of your skin; or
• blistering skin; or
• stretch marks.

What is Lexette?

Lexette foam is a super high potency, Class I corticosteroid foam that is applied to the skin to reduce inflammation and itching caused by plaque psoriasis in adults aged 18 years and older. Lexette contains halobetasol propionate 0.05%.

The foam is applied as a thin layer to the affected areas of the skin for a maximum of 2 consecutive weeks. Lexette foam is flammable, and you should avoid heat, open flames, or smoking while using this product. The canister may explode if it gets too hot. Do not puncture or burn an empty canister.

Lexette foam was FDA approved on May 24, 2018.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Lexette foam is a highly potent, Class I corticosteroid that can be absorbed through the skin into the bloodstream and cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency, including Cushing’s syndrome, hyperglycemia, and glucosuria. Do not use for longer than 2 weeks and do not use more than 50 grams per week. Periodic monitoring for HPA suppression may be required.

Before taking this medicine

You should not use Lexette if you are allergic to it.

Lexette foam should not be applied to lesions that are exuding serum or to skin folds (where two areas of skin touch each other).

Tell your doctor if you have ever had:

• any type of skin infection;
• a skin reaction to any steroid medicine;
• liver disease; or
• an adrenal gland disorder.

Topical corticosteroids can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

Children are more susceptible to systemic absorption of topical corticosteroids. Lexette foam is not approved for use by young adults and children under the age of 18.

It is not known whether Lexette foam will harm an unborn baby. Tell your doctor if you are pregnant. If you are instructed to use the foam, use a small amount for the shortest time possible.

It may not be safe to breastfeed while using this medicine. If you are instructed to Lexette foam, use a small amount for the shortest time possible. Do not apply to the breasts.

How do I use Lexette foam?

Use Lexette foam exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Do not take it by mouth. Topical medicine is for use only on the skin. Do not use on open wounds or sunburned, windburned, dry, or irritated skin. Rinse with water if it gets in your eyes or mouth.

• Wash your hands before and after using Lexette foam unless you are using this medicine to treat the skin on your hands.
• Shake the foam before each use.
• Press down on the actuator to dispense a small amount of foam into your hand.
• Apply a thin layer of Lexette foam to the affected area twice daily as directed by your doctor. Rub in gently and completely. Do not apply this medicine over a large area of skin unless your doctor has told you to.

Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.

Lexette foam is for short-term use only up to 2 weeks. Follow your doctor’s dosing instructions very carefully. Do not use more than 50 grams per week.

Call your doctor if your symptoms do not improve after 2 weeks, or if they get worse. Stop using the product if your symptoms improve sooner.

What happens if I miss a dose?

Apply the product as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line if anyone has accidentally swallowed the medication.

High doses or long-term use of Lexette foam can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using Lexette foam?

• Avoid heat, flame, or smoking during and right after applying Lexette to your skin, because it is flammable.
• Avoid applying Lexette foam to your face, scalp, underarms, or groin area.
• Do not use Lexette foam to treat any skin condition that has not been checked by your doctor.
• Avoid using other topical steroid medications on the areas you treat with Lexette foam unless your doctor tells you to.

What are the side effects of Lexette foam?

Get emergency medical help if you have signs of an allergic reaction to Lexette foam, such as hives; difficulty breathing; or swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• worsening of your skin condition;
• redness, warmth, swelling, oozing, or severe irritation of any treated skin;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• high blood sugar – increased thirst, increased urination, dry mouth, fruity breath odor; or
• possible signs of absorbing this medicine through your skin – weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Common Lexette side effects may include:

• headache
• pain where the foam was applied.

Other side effects reported with topical corticosteroids include:

• burning, stinging, itching, or dryness of treated skin
• redness or crusting around your hair follicles
• stretch marks
• spider veins.

Uses for Lidex

Fluocinonide topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. This medicine is a corticosteroid (cortisone-like medicine or steroid).

This medicine is available only with your doctor’s prescription.

Before using Lidex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fluocinonide topical in the pediatric population. However, because of this medicine’s toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using this medicine, follow your doctor’s instructions very carefully. For Vanos® cream, safety and efficacy have not been established in children younger than 12 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Vanos® cream in the elderly. However, elderly patients are more likely to have age-related medical problems, which may require caution in patients receiving Vanos® cream.

No information is available on the relationship of age to the effects of fluocinonide topical in geriatric patients.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Cushing’s syndrome (adrenal gland disorder) or
• Diabetes or
• Hyperglycemia (high blood sugar) or
• Intracranial hypertension (increased pressure in the head)—Use with caution. May make these conditions worse.

• Infection of the skin at or near the place of application or
• Large sores, broken skin, or severe skin injury at the place of application—The chance of side effects may be increased.

• Perioral dermatitis (skin problem) or
• Rosacea (skin problem)—Vanos® cream should not be used in patients with these conditions.

Proper use of Lidex

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

If you are using the Vanos® cream:

• Do not use it on the face, groin, or underarms unless directed to do so by your doctor.
• Do not use it for more than 2 weeks unless your doctor tells you otherwise.

To use:

• Wash your hands with soap and water before and after using this medicine.
• Apply a thin layer of this medicine to the affected area of the skin. Rub it in gently.
• Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.
• If the medicine is applied to the diaper area of an infant, do not use tight-fitting diapers or plastic pants unless directed to do so by your doctor.
• If your doctor ordered an occlusive dressing or airtight covering to be applied over the medicine, make sure you know how to apply it. Occlusive dressings increase the amount of medicine absorbed through your skin, so use them only as directed. If you have any questions about this, check with your doctor.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For topical dosage forms (cream, gel, ointment, or solution):
  • For redness, itching, and swelling of the skin:
    • Adults—Apply to the affected area of the skin two to four times per day.
    • Children—Apply to the affected area of the skin two to four times per day.
• For topical dosage form (cream):
  • For atopic dermatitis:
    • Adults and children 12 years of age and older—Apply to the affected area of the skin once a day.
    • Children younger than 12 years of age—Use is not recommended.
  • For psoriasis:
    • Adults and children 12 years of age and older—Apply to the affected area of the skin one to two times per day.
    • Children younger than 12 years of age—Use is not recommended.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions while using Lidex

It is very important that your doctor check the progress of you or your child at regular visits for any unwanted effects that may be caused by this medicine.

If your or your child’s symptoms do not improve within a few days, or if they become worse, check with your doctor.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.

Stop using this medicine and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.

Do not use cosmetics or other skin care products on the treated areas.

Side Effects of Lidex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

• Blistering, burning, crusting, dryness, or flaking of the skin
• irritation
• itching, scaling, severe redness, soreness, or swelling of the skin
• redness and scaling around the mouth
• thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g. between the fingers)
• thinning, weakness, or wasting away of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Fever
• headache
• muscle aches
• sore throat
• stuffy or runny nose
• unusual tiredness or weakness

Incidence not known

• Acne or pimples
• burning and itching of the skin with pinhead-sized red blisters
• burning, itching, and pain in hairy areas, or pus at the root of the hair
• increased hair growth on the forehead, back, arms, and legs
• lightening of normal skin color
• lightening of treated areas of dark skin
• reddish purple lines on the arms, face, legs, trunk, or groin
• softening of the skin

What is Luxiq?

Betamethasone is a highly potent steroid that prevents the release of substances in the body that cause inflammation.

Luxiq (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as eczema or psoriasis.

Luxiq may also be used for purposes not listed in this medication guide.

Luxiq side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Betamethasone may cause serious side effects. Stop using betamethasone and call your doctor at once if you have:

• severe skin irritation where the medicine was applied; or
• signs of skin infection (swelling, redness, warmth, oozing).

Your skin can absorb topical steroid medicine, which may cause steroid side effects throughout the body. Stop using betamethasone and call your doctor if you have:

• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• slow wound healing, thinning skin, increased body hair;
• increased thirst or urination, dry mouth, fruity breath odor;
• weight gain, puffiness in your face; or
• muscle weakness, tired feeling, depression, anxiety, feeling irritable.

Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using Luxiq.

Common side effects of Luxiq may include:

• itching, redness, burning, stinging, or blistering of treated skin;
• skin bruising or shiny appearance; or
• folliculitis (redness or crusting around your hair follicles).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA .

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Luxiq if you are allergic to it.

Tell your doctor if you have ever had:

• skin irritation after using steroid medicine;
• thinning of the skin where you will apply Luxiq;
• cataracts or glaucoma;
• diabetes;
• liver disease;
• adrenal gland problems; or
• any type of skin infection.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks. If you apply betamethasone to your chest, avoid areas that may come into contact with the baby’s mouth.

Do not use Luxiq on a child without a doctor’s advice. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

Diprolene is not approved for use by anyone younger than 13 years old. Sernivo and Luxiq are not approved for anyone younger than 18 years old.

How should I use Luxiq?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take by mouth. Topical medicine is for use only on the skin. Do not use on open wounds or on sunburned, windburned, dry, or irritated skin. Rinse with water if this medicine gets in your eyes or mouth.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Wash your hands before and after using this medicine, unless you are using the medicine to treat the skin on your hands.

Apply a small amount to the affected area and rub it gently into the skin. Do not apply Luxiq over a large area of skin.

Do not cover the treated skin area unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.

Use Luxiq regularly to get the most benefit. Stop using the medicine once your symptoms clear up.

Call your doctor if your skin condition does not improve after 2 weeks, or if it gets worse.

Do not use Diprolene for longer than 2 weeks in a row. Do not use  Sernivo or Luxiq for longer than 4 weeks.

Store at room temperature away from moisture and heat.

The foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.

What happens if I miss a dose?

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line if anyone has accidentally swallowed the medication.

Long term use of high doses can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using Luxiq?

Do not get Luxiq in your eyes. If contact does occur, rinse with water.

Avoid applying Luxiq to the skin of your face, underarms, or groin area without your doctor’s instruction.

Do not use Luxiq to treat any condition that has not been checked by your doctor.

What is Olux?

Clobetasol is a highly potent steroid that helps reduce inflammation in the body.

Olux (for the skin) is used to treat inflammation and itching caused by plaque psoriasis or skin conditions that respond to steroid medication.

Olux may also be used for purposes not listed in this medication guide.

Olux side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Olux may cause serious side effects. Call your doctor at once if you have:

• worsening of your skin condition;
• redness, warmth, swelling, oozing, or severe irritation of any treated skin;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• high blood sugar–increased thirst, increased urination, dry mouth, fruity breath odor; or
• possible signs of absorbing Olux through your skin–weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects of Olux may include:

• burning, itching, swelling, or irritation of treated skin;
• dry or cracking skin;
• redness or crusting around your hair follicles;
• spider veins;
• stretch marks, thinning skin;
• rash or hives;
• acne; or
• temporary hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Olux if you are allergic to it.

Tell your doctor if you have ever had:

• any type of skin infection;
• a skin reaction to any steroid medicine;
• liver disease; or
• an adrenal gland disorder.

Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

It is not known whether Olux will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply clobetasol to your chest, avoid areas that may come into contact with the baby’s mouth.

Olux is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.

Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

How should I use Olux?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth.

Do not use Olux on broken or infected skin. Also avoid using this medicine in open wounds.

Wash your hands before and after using clobetasol, unless you are using the medicine to treat the skin on your hands.

Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to.

Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.

If you are treating the diaper area, do not use plastic pants or tight-fitting diapers.

This medicine is for short-term use only (2 weeks, or up to 4 weeks for scalp psoriasis). Follow your doctor’s dosing instructions very carefully.

If you use clobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled.

Call your doctor if your symptoms do not improve, or if they get worse.

You should not stop using clobetasol suddenly. Follow your doctor’s instructions about tapering your dose.

Store at room temperature away from moisture and heat. Keep from freezing.

Clobetasol foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.

What happens if I miss a dose?

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

High doses or long-term use of Olux can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using clobetasol topical?

Avoid applying Olux to your face, underarms, or groin area.

Do not use this medicine to treat any condition that has not been checked by your doctor.

Avoid using other topical steroid medications on the areas you treat with clobetasol unless your doctor tells you to.