Aminopenicillins
What are Aminopenicillins?
Aminopenicillins are bactericidal beta-lactam antibiotics, which work by inhibiting bacterial cell wall synthesis. They are chemically similar to penicillin but have a broader spectrum of activity than penicillin. Aminopenicillins are not deactivated by acid hydrolysis so they can be administered orally, they are however susceptible to hydrolysis by beta-lactamase and therefore are sometimes given with beta-lactamase inhibitors. Aminopenicillins are effective against most gram-positive bacterial infections and gram-negative infections such as E.coli and H.influenza. They are used to treat upper and lower respiratory tract infections, endocarditis urinary tract infections, skin infections, and so on.
Aminopenicillins. Amoxicillin and ampicillin are 2 of the most commonly prescribed aminopenicillins. Immediate reactions are IgE-mediated to either the common β-lactam structure or the R-group side chain.
Ampicillin has more extended activity against aerobic gram-negative bacilli than penicillin, but an increasing number of strains of coliforms have become resistant to the drug. Penicillin and ampicillin are effective in both oral and parenteral formulations, and they are very inexpensive.
Penicillin is a class of antibiotic medications. Penicillins treat bacterial infections like strep throat, ear infections and urinary tract infections. They work by attaching to and damaging the cell walls of bacteria. Types of penicillin include penicillin V, penicillin G, amoxicillin and ampicillin.





