Calcium channel blockers

Other names: calcium antagonists, calcium channel antagonists, CCB

What are Calcium channel blockers?

Calcium channel blockers restrict the amount of calcium entering cardiac and smooth muscle cells by blocking voltage-gated calcium channels. This causes blood vessels to relax and widen (vasodilate), improves oxygen supply to the heart, and lowers blood pressure. Some calcium channel blockers also slow the heart rate. Calcium channel blockers are used to treat conditions of the heart or blood vessels including high blood pressure, angina, arrhythmias, and circulatory disorders.

Calcium channel blockers are medicines used to lower blood pressure. They stop calcium from entering the cells of the heart and arteries. Calcium causes the heart and arteries to squeeze more strongly. By blocking calcium, calcium channel blockers allow blood vessels to relax and open.

A change control board (CCB) is comprised of internal teams of subject matter experts (e.g., engineering, quality, purchasing, manufacturing) and often includes supply chain partners.

Calcium channel blockers (CCBs) prevent calcium from going into your artery walls. Your arteries use calcium for constriction, so blocking calcium leads to artery opening. CCBs are systemic vasodilators, not direct vasodilators.