Lymphatic staining agents
What are Lymphatic staining agents?
Lymphatic staining agents are injected subcutaneously to determine the location of lymphatic vessels draining from that area. This is often used in conjunction with lymphography to get a visualization of lymphatics in medical conditions involving the lymphatic system.
| Drug class | Agents | Effect |
|---|---|---|
| KATP channel openers | Minoxidil sulfate | Reduced lymph flow in vivo |
| Thiazolidinedione | Rosiglitazone | Tumor lymph vessel density was reduced in vivo |
| Rosiglitazone | Modest decreased lymphatic uptake in vivo | |
| Anthracyclines | Increased incidence of lymphedema in breast cancer patients |
The lymphatic system includes numerous structural components, including lymphatic capillaries, afferent lymphatic vessels, lymph nodes, efferent lymphatic vessels, and various lymphoid organs. Lymphatic capillaries are tiny, thin-walled vessels that originate blindly within the extracellular space of various tissues.
Some medications cause swollen lymph nodes as a side effect. These include: Some antibiotics (cephalosporins, sulpha drugs, penicillins)





