Ophthalmic glaucoma agents
What are Ophthalmic glaucoma agents?
Ophthalmic glaucoma agents are used to reduce eye pressure in glaucoma. Glaucoma refers to a group of eye conditions that lead to damage to the optic nerve, which in most cases, is due to increased pressure in the eye. More than one type of eye drop may be used at a time, and regular use is very important.
| Drug | Target | Type |
|---|---|---|
| Acetazolamide | Carbonic anhydrase 12 | target |
| Omidenepag isopropyl | Carboxylesterase | enzyme |
| Omidenepag isopropyl | Prostaglandin E2 receptor EP2 subtype | target |
| Omidenepag isopropyl | Prostaglandin E2 receptor EP1 subtype | target |
Due to the mechanisms of action previously discussed (see “Cholinergic Ocular Impact section”) cholinergic agonists (acetylcholine, carbachol, echothiopate Iodide, and pilocarpine), are widely used in glaucoma management.
Eye drops for glaucoma may affect how those other medicines work. Some types of eye drops work by helping fluid drain from your eye, which lowers eye pressure. Examples include: Prostaglandins, like Xalatan (latanoprost), Travatan Z (travoprost), Zioptan (tafluprost), and Lumigan (bimatoprost)





