Progestins are synthetic steroid hormones that activate the progesterone receptor in a similar way to progesterone but each individual progestin has its own distinctive effect.
The progestins are used to treat amenorrhea, premenstrual tension and abnormal uterine bleeding. As they prevent ovulation, progestins are a major constituent of oral contraceptives and other forms of contraception. Progestins can also act to decrease levels of some hormones so can be used to treat hormonally sensitive cancers, for transgender hormone suppression and for precocious puberty.
Progestins, synthetic compounds emulating the action of progesterone, serve a pivotal role in various medical applications, spanning from contraception to postmenopausal hormone replacement therapy. These medications interact with progesterone receptors, exhibiting distinct effects based on their generational classification or structural composition. This comprehensive review delves into the mechanism of action, indications, contraindications, and potential adverse events associated with progestin therapy. Aimed at healthcare professionals involved in patient care, this activity elucidates critical facets of progestin usage, ensuring a comprehensive understanding to enable effective management of various conditions where progestins may offer therapeutic benefits.
