Therapeutic vaccines

What are Therapeutic vaccines?

Therapeutic vaccines are vaccines which are intended to treat or cure a disorder or disease by stimulating the immune system. Therapeutic vaccines may be used to treat certain types of cancer, by stimulating the body’s immune system to help it respond against certain cancer cells. They may also be used in the prevention of tuberculosis in persons not previously infected with M. tuberculosis who are at high risk for exposure.

What are the types of vaccines?

There are several types of vaccines:

Live-attenuated vaccines use a weakened form of the germ.
Inactivated vaccines use a killed version of the germ.
Subunit, recombinant, polysaccharide, and conjugate vaccines use only specific pieces of the germ, such as its protein, sugar, or casing.
Toxoid vaccines use a toxin (harmful product) made by the germ.
mRNA vaccines use messenger RNA, which gives your cells instructions for how to make a protein (or piece of a protein) of the germ.
Viral vector vaccines use genetic material, which gives your cells instructions for making a protein of the germ. These vaccines also contain a different, harmless virus that helps get the genetic material into your cells.

What happens in an immune response?

There are different steps in the immune response:

When a germ invades, your body sees it as foreign.
Your immune system helps your body fight off the germ.
Your immune system also remembers the germ. It will attack the germ if it ever invades again. This “memory” protects you against the disease that the germ causes. This type of protection is called immunity.

What are immunization and vaccination?

Immunization is the process of becoming protected against a disease. But it can also mean the same thing as vaccination, which is getting a vaccine to become protected against a disease.

Why are vaccines important?

Vaccines are important because they protect you against many diseases. These diseases can be very serious. So getting immunity from a vaccine is safer than getting immunity by being sick with the disease.

For a few vaccines, getting vaccinated can actually give you a better immune response than getting the disease would.

But vaccines don’t just protect you. They also protect the people around you through community immunity.

What is community immunity?

Community immunity, or herd immunity, is the idea that vaccines can help keep communities healthy.

Normally, germs can travel quickly through a community and make a lot of people sick. If enough people get sick, it can lead to an outbreak. But when enough people are vaccinated against a certain disease, it’s harder for that disease to spread to others. This type of protection means that the entire community is less likely to get the disease.

Community immunity is especially important for people who can’t get certain vaccines. For example, they may not be able to get a vaccine because they have weakened immune systems. Others may be allergic to certain vaccine ingredients. And newborn babies are too young to get some vaccines. Community immunity can help to protect them all.

Are vaccines safe?

Vaccines are safe. They must go through extensive safety testing and evaluation before they are approved in the United States.

What is a vaccine schedule?

A vaccine, or immunization, schedule lists which vaccines are recommended for different groups of people. It includes who should get the vaccines, how many doses they need, and when they should get them. In the United States, the Centers for Disease Control and Prevention (CDC) publishes the vaccine schedule.

It’s important for both children and adults to get their vaccines according to the schedule. Following the schedule allows them to get protection from the diseases at exactly the right time.

A therapeutic vaccine differs from a prophylactic vaccine in that prophylactic vaccines are administered to individuals as a precautionary measure to avoid the infection or disease while therapeutic vaccines are administered after the individual is already affected by the disease or infection.

To be immune is to be partially or fully resistant to a specific infectious disease or disease-causing organism. A person who is immune can resist the bacteria or viruses that cause a disease, but the protection is never perfect.

Although an effective prophylactic vaccine already exists against HPV, the goal of a therapeutic vaccine would be to destroy cells which have already been infected with the virus and begun to transform into precancerous or cancerous cells.

Prophylactic antibiotic coverage is indicated for clean contaminated or contaminated surgical procedures, and dirty wounds need both prophylactic and therapeutic antibiotic use. The most effective administration route of prophylactic antibiotics remains a matter of discussion.