CD52 monoclonal antibodies 

What are CD52 monoclonal antibodies?

Monoclonal antibodies used in immunotherapy are produced artificially from a cell clone therefore consist of a single type of immunoglobulin. They are targeted towards specific antigens and bind to the antigens to form a complex. The complex can be recognized and destroyed by phagocytes or used for other diagnostic purposes.

Natural antibodies are proteins made by the B-lymphocytes in response to antigens. Each B-cell makes only one type of antibody. For therapeutic purposes a significant amount of a particular antibody is needed. These are obtained from a culture that gives a one type of antibody, which are called monoclonal antibodies.

CD52 antigens are present on lymphocytes. CD52 monoclonal antibodies bind to CD52 antigens and bring about complement and antibody-dependent cell-mediated cytotoxicity. CD52 monoclonal antibodies are used to treat patients with B-cell chronic lymphocytic leukemia (B-CLL).

Clone Campath-1H is a monoclonal antibody that specifically binds to CD52, a protein present on the surface of mature lymphocytes. However, this protein is not present on the stem cells that generated these lymphocytes.

List of CD52 monoclonal antibodies

Cabenuva

Cabenuva

Cabometyx

Cabometyx

Calcitriol

Calcitriol

Calquence

Calquence

Camzyos

Camzyos

Canasa

Canasa

Candesartan

Candesartan

Caplyta

Caplyta

Captopril

Captopril

Carvedilol

Carvedilol

Carvykti

Carvykti

Casodex

Casodex

Cefdinir

Cefdinir

Cefixime

Cefixime

Ceftriaxone

Ceftriaxone

Celebrex

Celebrex

Celecoxib

Celecoxib

Celexa

Celexa

Cephalexin

Cephalexin

Cetirizine

Cetirizine

Cialis

Cialis

Cimzia

Cimzia

Cinryze

Cinryze

Cipro

Cipro

Citalopram

Citalopram

Claritin

Claritin

Clindamycin

Clindamycin

Clobetasol

Clobetasol

Clobex

Clobex

Clodan

Clodan

Clonazepam

Clonazepam

Clopidogrel

Clopidogrel

Clotrimazole

Clotrimazole

Clozapine

Clozapine

Cobenfy

Cobenfy

Codeine

Codeine

Colace

Colace

Colazal

Colazal

Colchicine

Colchicine

Concerta

Concerta

Coreg

Coreg

Crestor

Crestor